Wrike is an application that focuses solely on project management, and does not really have any help desk components. Here is a side-by-side feature comparison between OneDesk and Wrike.

In terms of pricing, with Wrike you need to figure out which features are in which plans and which add-ons. Then you need to call for pricing in most cases since only their-lowest level plans have published pricing.

With OneDesk you pay a flat fee for ALL our features, we do not make you purchase and connect multiple applications, modules, or plans. Our pricing is published and clear and ranges from $4-6 per user per month.

Price$6.50 - $11 per user/month$10/user/month - up to - multiple levels of unpublished pricing, plus add-ons
Tasks and Sub-tasksincludedYes
Gantt chartsincludedYes
Attachment storageincluded5-100GB depending on price plan
Custom FieldsincludedOnly in $25/user plan
Custom StatusesincludedOnly in $25/user plan
ReportsincludedOnly in $25/user plan
CalendarsincludedOnly in $25/user plan
Custom Request FormsincludedOnly in $25/user plan
Time TrackingincludedOnly in $25/user plan
TeamsincludedIn Enterprise plan ($$$?)
Active Directory IntegrationincludedIn Enterprise plan ($$$?)
SAML SSOincludedIn Enterprise plan ($$$?)
TimesheetsincludedIn Enterprise plan ($$$?)
Create task by emailincludedYes
Activity LogincludedTask status changes only
Full Helpdesk FunctionalityincludedNo
Live ChatincludedNo
Knowledge BaseincludedNo
Custom viewsincludedNo
Client PortalincludedNo
Email tracking for incoming & outgoingincluded - last 72 hoursNo
IntegrationsincludedRequired a paid add-on ($?)